Endorphinate® Product Information

 Endorphinate® is the only available safe and natural way to enhance and balance endorphins, critical to the restoration and maintenance of healthy stress and pain responses.

ENDORPHINATE® AR

Vegetarian Active Ingredients:  N-Acetyl Cysteine, Bio-Curcumin (BCM-95®), L-Theanine (L-TeaActive™), Green Tea (99% natural caffeine), Folate, Vitamin B-12, Vitamin B-6. Vegetarian inactive ingredients: rice bran, ascorbyl palmitate. Vegetarian capsules: vegetable cellulose. (Please note that the AR formula now contains Bio-Curcumin (BCM-95®), an extract of turmeric, and, since turmeric is yellow, the AR capsules are now yellow)

  • What are the benefits? Most people can benefit from daily use of Endorphinate® AR for
    • Reduction of anxiety, anger, cravings, and addictions.
    • Reduction of emotional and physical distress.
    • Enhanced adaptive response to many types of stress.
    • Increased calm, comfort, energy, positive mood, concentration, and well-being.
    • Improved emotional, interpersonal, sexual, and mental functioning.
    • Greater self-control over feelings, thoughts, behaviors, and substance use.
  • How quickly will you experience the benefits of Endorphinate®?
    • Some individuals report benefits within minutes, hours, and days of initial dosing.
    • Others find that their benefits are experienced more slowly over the first few weeks.
    • Major benefits typically continue to increase over months of daily use.
  • How much Endorphinate® AR should you take? Although many people receive the benefits they require from two capsules daily, some find that they prefer four capsules daily. Most people start with one capsule, twice daily, and many then increase to two capsules, twice daily.  Some people find that up to six capsules taken throughout the day provides them enhanced benefits.
  • Energizing effects. Endorphinate® AR stimulates endorphin production, which promotes mental energy and alertness as well as serenity and well-being.  For those sensitive to its energizing effects, we suggest taking the initial daily dose upon awakening and the last dose by mid-afternoon, or consider using Endorphinate® CF (caffeine-free), which has less energizing effects.
  • Restful sleep. Most people have restful sleep when taking daily Endorphinate® AR.  For continued sleep concerns, Endorphinate® CF can be taken before bedtime to promote restful sleep.
  • Side effects. Endorphinate® AR is well tolerated by most individuals.  The only side effects reported (by less than 5% of respondents to our survey) were sleep-related. These concerns were resolved by using only CF in the evening.
  • Other drugs. Endorphinate® has been used successfully with a wide variety of prescription and over-the-counter pain, anxiety, depression, sleep, addiction and other medications. However, if you are taking other medications, please consult your health care practitioner before Endorphinate®.
  • Treatment of Disease. Endorphinate AR is not intended to diagnose, treat, cure, or prevent any disease.

ENDORPHINATE® CF

Vegetarian Active Ingredients:N-Acetyl Cysteine, L-Theanine (L-TeaActive), RVegetarian inactive ingredients: rice bran, ascorbyl palmitate. Vegetarian capsules: vegetable cellulose.

  • What are the benefits? Almost everyone can benefit from daily use of Endorphinate® CF for
    • Improved restful sleep.
    • Increased calm, comfort, positive mood, and well-being.
    • Relief from anxiety, anger, and cravings.
    • Prevention of emotional and physical distress.
    • Enhanced adaptive response to many types of stress.
    • Greater self-control over feelings, thoughts, and behaviors.
  • How quickly will you experience the benefits of Endorphinate®?
    • Some individuals report benefits within minutes, hours, and days of initial dosing.
    • Others find that their benefits are experienced more slowly over the first few weeks.
    • Major benefits typically continue to increase over months of daily use.
  • Restful sleep. When taken at bedtime, Endorphinate® CF can promote restful sleep.  Most people start with one capsule, but may increase to two capsules for extra strength.  Many people take Endorphinate® AR or PR during the day for their energizing and anti-inflammatory benefits, and use Endorphinate® CF at bedtime for restful sleep.
  • Daily calm and well- For people who are sensitive to, or prefer not to have the energizing effects of Endorphinate® AR and PR (both contain caffeine), Endorphinate® CF can be taken during the day as well as at bedtime.  For this purpose, many people receive the benefits they require from two capsules daily.  Others find that they prefer four capsules daily.  Some people find that up to six capsules taken throughout the day provides enhanced benefits.
  • Side effects. Endorphinate® CF is well tolerated by most individuals.  No negative side effects have been reported.
  • Other drugs. Endorphinate® has been used successfully with a wide variety of prescription and over-the-counter pain, anxiety, depression, sleep, addiction and other medications. However, if you are taking other medications, please consult your health care practitioner before Endorphinate®.
  • Treatment of Disease. Endorphinate CF is not intended to diagnose, treat, cure, or prevent any disease.

 ENDORPHINATE® PR

Vegetarian Active Ingredients:White Willow Bark, N-Acetyl Cysteine, Guarana Extract, L-Theanine (L-TeaActive) Boswellia Extract (Apres-Flex™), Magnesium Sulfate, Pyridoxal 5 Phosphate (P5P) Folic Acid, Vitamin B-12.  Vegetarian inactive ingredients: rice bran, ascorbyl palmitate. Vegetarian capsules: vegetable cellulose.

  • What are the benefits? Endorphinate® PR helps promote
    • A reduction in inflammation and minor pain unassociated with any disease state, i.e. muscle pain following exercise.
    • Relief from tension, anxiety, anger, and cravings.
    • Reduced physical and emotional distress due to endorphin imbalances & inflammation.
    • Enhanced adaptive response to many types of stress.
    • Increased comfort, calm, energy, positive mood, concentration, and well-being.
    • Improved emotional, interpersonal, sexual, and mental functioning.
    • Greater self-control over feelings, thoughts, behaviors, and substance use.
  • How quickly will you experience the benefits of Endorphinate®?
    • Some individuals report benefits within minutes, hours, and days of initial dosing.
    • Others find that their benefits are experienced more slowly over the first few weeks.
    • Major benefits typically continue to increase over months of daily use.
  • How much Endorphinate® PR should you take? Although many people receive the benefits they require from two capsules daily, some find that they prefer four capsules daily. Most people start with one capsule, twice daily, and many then increase to two capsules, twice daily.  Some people find that up to six capsules taken throughout the day provides them desired personal benefits.
  • Energizing effects.  Endorphinate® PR stimulates endorphin production, which promotes mental energy and alertness as well as serenity and well-being.  For those sensitive to caffeine, we suggest taking the initial daily dose upon awakening and the last dose by mid-afternoon, or consider using caffeine-free Endorphinate® CF.
  • Restful sleep. Most people have restful sleep when taking daily Endorphinate® PR.  For continued sleep concerns, Endorphinate® CF can be taken before bedtime to promote restful sleep.
  • Side effects. Endorphinate® PR is well tolerated by most individuals.  The only side effects reported (by less than 5% of respondents to our survey) were sleep-related. These concerns were resolved by using only CF in the evening.
  • Other drugs. Endorphinate® has been used successfully with a wide variety of prescription and over-the-counter pain, anxiety, depression, sleep, addiction and  other medications. However, if you are taking other medications, please consult your health care practitioner before Endorphinate®.
  • Treatment of Disease. Endorphinate PR is not intended to diagnose, treat, cure, or prevent any disease.

How Does Endorphinate Work FAQ: How Does Endorphinate Work FAQ

What are the results of the 315 anonymous on-line surveysEndorphinate On-line Survey Report

Order Issues: Contact Customer Service: info@ponderapharma.com or (877) 865-6926 Clinical Issues:  Contact Dr. Steven Crain: drstevencrain@aol.com or (814) 769-1980 Returns:  Pondera Pharmaceuticals, 209 Chadsey Road, Pownal ME 04069 (100% refund)

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